- Combo Therapy for Vitiligo
Combo Therapy for Vitiligo
Bottom Line: Patients with the skin depigmentation disease known as vitiligo had faster and better repigmentation after a combination therapy of the implantable drug afamelanotide and narrowband UV-B (NB-UV-B) phototherapy as part of a clinical trial.
Author: Henry W. Lim, M.D., of Henry Ford Hospital, Detroit, Mich., and colleagues.
Background: Vitiligo is characterized by white patches of skin and affects 1 percent to 2 percent of the population. The authors report the results of a multicenter randomized clinical trial comparing the safety and effectiveness of the combination therapy with the phototherapy alone in 55 patients.
How the Study Was Conducted: The study was performed in two academic outpatient dermatology centers and one private dermatology office. The combination therapy group included 28 patients and the NB-UV-B monotherapy group had 27 patients assigned.
Results: Results were better in the combination therapy group than in the monotherapy group at day 56. For the face and upper extremities, more patients achieved repigmentation at a faster rate (face, 41 vs. 61 days; upper extremities, 46 vs. 69 days). In the combination therapy group, repigmentation was 48.64 percent at day 168 compared with 33.26 percent in the monotherapy group.
Discussion: “The results of this study offer hope to patients with vitiligo in the treatment of this disfiguring disease.”
(JAMA Dermatology. Published online September 17, 2014. doi:10.1001/jamadermatol.2014.1875.
DISCLAIMER: Bankix Systems Ltd is the registered name of a Canadian firm since 2003, and bankixsystems.com is its OFFICIAL website. Besides these entities, we have no relationship with anyone, business, website, or any other entity anywhere in the world, claiming to be Bankix Systems, or using a similar name, and creating the impression that it has some connection with our company. We do not endorse and are therefore, not responsible for any act or lack thereof by any such entity. Bankix Systems Ltd is also not responsible for the content of the description of products and services linked to our site nor does it necessarily endorse them. The information here provided is not for diagnosing/treating your health concerns. Kindly contact your doctor or health care professional for all your healthcare requirements.
Contents © 2003-2018, BankixSystems.com. All rights reserved. Unauthorized reproduction strictly prohibited. Information based on best available resources. Opinions are current and subject to change.